FORMULATION OF SARS-COV-2 SPIKE PROTEIN WITH CPG OLIGODEOXYNUCLEOTIDES AND SQUALENE NANOPARTICLES MODULATES IMMUNOLOGICAL ASPECTS FOLLOWING INTRANASAL DELIVERY

Nasal spray vaccination is viewed as a promising strategy for inducing both mucosal and systemic protection against respiratory SARS-CoV-2 coronavirus.Toward this goal, a safe and efficacious mucosal adjuvant is necessary for the transportation of the antigen across the mucosal membrane and antigen recognition by the mucosal immune system to genera

During meiosis, the rapid movement of telomeres along the nuclear envelope (NE) facilitates pairing/synapsis of homologous chromosomes.In mammals, the mechanical properties of chromosome movement and the cytoskeletal structures responsible for it remain poorly understood.Here, applying an in vivo electroporation (EP) technique in live mouse testis,

For decades, the water hyacinth (WH) has progressively proven to be a prevalent invasive plant with significant environmental and socio-economic impacts.Its successful proliferation is enhanced by climate and hydrodynamic conditions (i.e., temperature, water flow regime, nutrient load) which strengthen the intrinsic characteristics of reproduction

Adoptive transfer of chimeric antigen receptor-transduced T cells is a promising strategy for cancer immunotherapy.The CD38 molecule, with its high expression on multiple myeloma cells, appears a suitable target for antibody therapy.Prompted by this, we used three different CD38 antibody sequences to generate second-generation retroviral CD38-chime

In this paper, we examine students’ reflections about the value of two photo-sharing activities that were implemented in undergraduate Biology and Chemistry subjects.Both activities aimed, broadly, to provide support for authentic and meaningful learning experiences in undergraduate science.Although the activities were similar – both